Why Everyone Should Be Taking This Little-Known Enzyme

What is Nattokinase?

Nattokinase is a type of proteolytic enzyme that is derived from the Japanese food natto, a traditional dish made from fermented soybeans. Natto has been a staple in Japanese diets for centuries and is known for its many health benefits, including its ability to improve cardiovascular health.

Nattokinase works by breaking down fibrin, a protein involved in blood clotting. Fibrin can build up in the blood vessels over time, leading to the formation of blood clots that can cause heart attacks and strokes. Nattokinase may help prevent blood clots from forming and improve blood flow, making it a potentially useful supplement for individuals with cardiovascular or circulatory issues.

Benefits of Nattokinase

• Improved Cognitive Function

Some studies have suggested that nattokinase may improve cognitive function and protect against cognitive decline in older adults. One study published in the Journal of Agricultural and Food Chemistry found that nattokinase supplementation improved cognitive function in mice with induced dementia.

• Reduced Risk of Cancer

Some studies have suggested that nattokinase may have anti-cancer properties. One study published in the Journal of Natural Products found that nattokinase inhibited the growth of human cancer cells in vitro.

Nattokinase may be able to inhibit the growth of cancer cells in vitro and in animal models. For example, a study published in the International Journal of Oncology found that nattokinase suppressed the growth and invasion of human lung cancer cells by reducing the expression of certain genes involved in tumor growth and metastasis.

Another study published in the Journal of Medicinal Food found that nattokinase had anti-tumor effects in mice with melanoma, a type of skin cancer, by inducing apoptosis (programmed cell death) in cancer cells and inhibiting their proliferation.

• Improved Cardiovascular Health

Nattokinase has been shown to improve cardiovascular health by reducing the risk of blood clots, improving circulation, and reducing blood pressure. Studies have also shown that nattokinase may reduce the risk of heart disease and stroke.

One study published in the journal Hypertension Research found that nattokinase supplementation reduced both systolic and diastolic blood pressure in individuals with hypertension. Another study published in the Journal of Nutritional Science and Vitaminology found that nattokinase supplementation improved blood flow and reduced blood pressure in healthy individuals.

• Reduced Inflammation

Inflammation is a natural response to injury or infection, but chronic inflammation can lead to a host of health problems, including cardiovascular disease. Nattokinase has been shown to have anti-inflammatory properties, which may help reduce inflammation throughout the body.

One study published in the Journal of Medicinal Food found that nattokinase supplementation reduced inflammation and oxidative stress in individuals with metabolic syndrome. Another study published in the Journal of Atherosclerosis and Thrombosis found that nattokinase reduced inflammation in the blood vessels and improved blood flow in individuals with atherosclerosis.

• Improved Brain Function

The brain is highly dependent on blood flow, and poor circulation can lead to cognitive decline and other brain-related issues. Nattokinase may improve blood flow to the brain, potentially improving cognitive function and reducing the risk of age-related cognitive decline.

One study published in the Journal of Alzheimer’s Disease found that nattokinase supplementation improved cognitive function in individuals with mild cognitive impairment. Another study published in the Journal of Stroke and Cerebrovascular Diseases found that nattokinase improved blood flow to the brain and reduced the risk of stroke in individuals with atrial fibrillation.

• Reduced Risk of Osteoporosis

Osteoporosis is a condition characterized by low bone density and an increased risk of fractures. Some studies have suggested that nattokinase may help improve bone density and reduce the risk of osteoporosis.

One study published in the Journal of Nutritional Science and Vitaminology found that nattokinase supplementation improved bone density and reduced the risk of osteoporosis in postmenopausal women. Another study published in the Journal of Medicinal Food found that nattokinase reduced bone loss in rats with estrogen deficiency.

• Possibly Prevent Strokes

Nattokinase has been studied for its potential role in stroke prevention. Blood clots that form in the brain can cause ischemic strokes, which occur when blood flow to the brain is blocked. Nattokinase has been shown to have a fibrinolytic effect, meaning it can break down fibrin, a protein that plays a key role in blood clotting.

A study published in the journal Hypertension Research found that nattokinase supplementation reduced blood pressure and improved blood flow in patients with hypertension, which is a major risk factor for stroke. Another study published in the Journal of Agricultural and Food Chemistry found that nattokinase reduced the risk of blood clots in mice with induced stroke.

It has found to be effective in dissolving blood clots, which is why it is often used as a natural alternative to traditional blood-thinning medications. Blood clots can form in blood vessels and can cause serious health problems, such as deep vein thrombosis, stroke, or heart attack.

Studies have shown that nattokinase has a powerful fibrinolytic activity, which means it can dissolve fibrin, a protein that is an essential component of blood clots. This activity has been shown to be effective in breaking down blood clots in the body, preventing their formation, and improving circulation.

A 2008 study published in the journal Acta Haematologica found that nattokinase significantly reduced blood clot formation in healthy individuals. Another study published in the Journal of Clinical Biochemistry and Nutrition found that nattokinase supplementation helped dissolve blood clots in patients with deep vein thrombosis.

While more research is needed to fully understand the potential benefits of nattokinase for dissolving blood clots, the results of these studies are promising.

Potential Side Effects and Precautions

While nattokinase is generally considered safe, some individuals may experience side effects such as stomach upset or allergic reactions. Additionally, nattokinase may interact with certain medications, such as blood thinners, and should be avoided by individuals with bleeding disorders or those undergoing surgery.

How to Take Nattokinase

Nattokinase supplements are widely available in health food stores and online retailers. They come in a variety of forms, including capsules and tablets.

It is recommended to take nattokinase supplements on an empty stomach, as food may interfere with its absorption. The appropriate dosage may vary depending on the individual and their specific health concerns. It is important to follow the recommended dosage instructions on the supplement label or as directed by a healthcare provider.

In addition to its potential benefits, nattokinase has also been found to improve overall cardiovascular health. It may help reduce high blood pressure, improve circulation, and reduce inflammation throughout the body.

Definitely a daily supplement must-have in my opinion! This is not medical advice but there you have it.